Endocrine Abstracts

Aim: To study the results of transsphenoidal surgery in our Neuroendocrinology Unit in last 10 years.Methods: We reviewed all patients operated in our hospital and followed in our Neuroendocrinology Unit in the last 10 years. We excluded patients with previous surgery or irradiation on this area. We obtained data about type and size of tumor, previous hormonal deficit, local symptoms,complications of surgery and the status after this (remission, persiste...

Aims: To know characteristics and long term evolution of patients with prolactinoma in our Neuroendocrinology Unit.Material and methods: We studied retrospectively all patients with diagnosis of prolactinoma in our Neuroendocrinology Unit in last 12 years.Results: We studied 126 patients. Predominant sex was female (69.07%), 56.7% were macroadenomas. The time from the onset of symptoms until they are seen by the specialist ranges 1...

Introduction: The recombinant GH receptor antagonist pegvisomant (PGV) is actually used for the treatment of acromegaly when surgery and medical therapy with somatostatin analogues (SSA) have failed. Long term safety and effectiveness need to be evaluated.Material and methods: Retrospective analysis of clinical data from all patients treated with pegvisomant in a pituitary disorders unit.Results: Thirteen patients are being treated...

Objective: To report a case of hyperandrogenism attributable to the presence of an ovarian Leydig cell tumor secreting testosterone in a postmenopausal woman.Methods: The laboratory, radiologic, and pathologic findings in our case are described.Results: A 59-year-old woman presented with a history of gradual increase in facial and body hair, scalp hair loss, male pattern baldness, and deepening of her voice, beginning 5–6 year...

Introduction and objetives: There are few data in literature about the effects of rosuvastatin in patients with familial hypercholesterolemia in Spain. The objective of this study has been:1-to evaluate the efficacy and security of rosuvastatin in patients with familiar hypercholesterolemia2-to test the hypothesis that patients with diabetes have different response to treatment with rosuvastatin.Material and ...

Introduction: Patients with bariatric surgery require close monitoring because of possible metabolic complications. It has been published some cases of severe and persistent hypoglycemias resistant to diet and pharmacologic treatment being necessary a pancreatectomy. We present a case report of nesidioblastosis after gastric bypass that required subtotal pancreatectomy but despite this, hypoglycemias persisted. Before performing total pancreatectomy we placed a tube feeding in...

Objective: Calculation of accurate insulin boluses is one of the major problems related to intensive insulin regimens. A bolus calculator (BC) incorporated into the insulin pump estimates the dose of insulin to be administered at the meal and makes calculation easier and more precise.The aim of the present study was to assess the efficacy of a BC on glycaemic control of patients with DM1 on CSII.Material and methods: We enrolled 20...

Objective: Our objective in this study was to identify the type of clinical care received by young type 1 diabetic patients who have made the transition from paediatric to adult care, and to assess the metabolic status of the patients. The research aimed to develop a sustainable and coordinated approach to facilitating the transition between diabetes services for adolescents and reveal from the perspective of the adolescents living with type 1 diabetes their experiences surrou...

Introduction: Pregestational diabetes is a threatening condition for pregnancy; a strict glycemic control can decrease some pregnancy complications. That control can be achieved while on multiple daily insulin injections (MDI) treatment or with subcutaneous insulin infusion systems (CSII). Up to now no benefits of CSII treatment over MDI on pregnancy outcomes have been proved.Design: Case control retrospective study, comparing glycemic control and pregna...

Introduction: Telehealth systems have become an alternative method to control chronic illnesses like diabetes. The aim of this study was to evaluate a telehealth system in patients with type 1 diabetes who have an optimized treatment with an insulin pump and real-time continuous glucose monitoring system.Research design and methods: Prospective, 1-year study of 15 patients with a continuous insulin infusion system and a real time glucose sensor. Three me...